OBJECTIVES:

The aim of this study was to evaluate ovarian function with longitudinal changes in serum levels of anti-mullerian hormone (AMH), follicle stimulating hormone (FSH) and estradiol (E2) after total abdominal hysterectomy (TAH) with ovarian conservation.復(fù)旦大學附屬婦產(chǎn)科醫(yī)院婦科史穎莉

MATERIAL AND METHODS:

In this prospective longitudinal study, atotal of 29women, aged 39 to 48years, suffering from uterine pathologies underwent TAH with ovarian conservation. Their serum AMH, FSH and E2 levels were measured at baseline, at the first month and the third month after TAH.

RESULTS:

There was astatistically significant decrease in AMH serum levels between the baseline and the first postoperative month; the values were 0.22 (0.16-1.49) ng/mL and 0.18 (0.04-0.52) ng/mL, respectively. However, significant differences were not seen for serum levels of FSH and E2 when baseline and one-month values were compared. In addition, no statistically significant differences were detected between the baseline and third-month serum AMH, FSH and E2 levels.

CONCLUSIONS:

The study demonstrated that TAH affects ovarian function temporarily.